Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• ]. Antioxidants contribute to cancer inhibition and cancer treatment by several mechanisms. First, nanoantioxidants reduce cancer initiation by protecting DNA molecules from oxidative stress and stimulating DNA repair. For example, platinum nanoparticles inhibited the growth of epithelial lung cancer cells by

• is caused by protein denaturation at high temperatures. Impressively, Co3O4 nanomaterials with different morphologies (nanoplates, nanorods, and nanocubes) exhibited the highest relative activity at very high pH (pH 9) and temperature (90 °C) [39]. Similar results were also reported for platinum

• nanoparticles whose H2O2 decomposition increased with increasing pH values (up to 11) and temperatures (up to 90 °C) [40]. The activity of natural CAT can also be improved by immobilizing it on nanomaterials. Immobilized CAT on Cu(II) nanofibers maintained approximately half of its catalytic activity after

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• particle size from 50 to 4.98 nm. In another study, the size-dependent photothermal conversion efficiency of platinum nanomaterials was studied by Depciuch et al. for cancer therapy. Spherical platinum nanoparticles with diameters of 2 and 80 nm were studied regarding the photothermal activity in colon

• Chemical Society. This content is not subject to CC BY 4.0.). Photothermal conversion efficiency of 2 and 8 nm platinum nanoparticles. Orange and the red line represent 2 and 80 nm Pt nanoparticles respectively and their calculated abs/ext ratio (B). (Figure 5B was reprinted from [54], Photodiagnosis and

• Photodynamic Therapy, vol. 29, by J. Depciuch; M. Stec; B. Klebowski; A. Maximenko; E. Drzymała; J. Baran; M. Parlinska-Wojtan, “Size effect of platinum nanoparticles in simulated anticancer photothermal therapy“, article no. 101594, Copyright (2019), with permission from Elsevier. This content is not subject

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

A novel approach to pulsed laser deposition of platinum catalyst on carbon particles for use in polymer electrolyte membrane fuel cells

• Bogusław Budner,
• Wojciech Tokarz,
• Sławomir Dyjak,
• Andrzej Czerwiński,
• Bartosz Bartosewicz and
• Bartłomiej Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 190–204, doi:10.3762/bjnano.14.19

• an efficient Pt-based catalyst for polymer electrolyte membrane fuel cells (PEMFCs) by using a cost-effective and efficient physical method to deposit platinum nanoparticles (PtNPs) on carbon supports directly from the platinum target. The method developed avoids the chemical functionalization of the

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• ssDNA recognition elements [31]. As per our observation, this is the first application of an electrochemical DNA biosensor for BT detection. Kusnin et al. [57] employed silicon nanowires/platinum nanoparticles (SiNWs/PtNPs) on a SPCE for the detection of porcine DNA. The few studies conducted earlier

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

Recent progress in actuation technologies of micro/nanorobots

• Ke Xu and
• Bing Liu

Beilstein J. Nanotechnol. 2021, 12, 756–765, doi:10.3762/bjnano.12.59

• reactive substances formed on the surface of the biofilm. The robot is composed of biocompatible materials, and the internal structure is decorated with platinum nanoparticles, which can decompose H2O2 fuel into bubbles. The characteristics of the tubular microrobot are illustrated in Figure 2. The bubbles

Stability and activity of platinum nanoparticles in the oxygen electroreduction reaction: is size or uniformity of primary importance?

• Kirill O. Paperzh,
• Anastasia A. Alekseenko,
• Vadim A. Volochaev,
• Ilya V. Pankov,
• Olga A. Safronenko and
• Vladimir E. Guterman

Beilstein J. Nanotechnol. 2021, 12, 593–606, doi:10.3762/bjnano.12.49

• . Keywords: durability; electrocatalysts; morphology control; oxygen reduction reaction; platinum nanoparticles; size distribution; spatial distribution; Introduction Nowadays, low-temperature proton-exchange membrane fuel cells (PEMFC) are gaining a wider application. This is due to their environmental

• hydrogen oxidation or an organic reducing agent oxidation (e.g. methanol) occur [4][5]. The need to carry out high-rate electrode reactions requires electrocatalysts (i.e., platinum nanoparticles – NPs – or its alloys), deposited mainly onto nano/microparticles of carbon supports, which are currently the

• ]. Later, it was shown that the effect of the platinum NP size on the specific surface activity was much weaker than it seemed to be at first. For example, according to the results presented in [14], with a decrease in the average size of platinum nanoparticles (i.e., from 5–6 to 1–2 nm) the specific ORR

Alloyed Pt₃M (M = Co, Ni) nanoparticles supported on S- and N-doped carbon nanotubes for the oxygen reduction reaction

• Stéphane Louisia,
• Yohann R. J. Thomas,
• Pierre Lecante,
• Marie Heitzmann,
• M. Rosa Axet,
• Pierre-André Jacques and
• Philippe Serp

Beilstein J. Nanotechnol. 2019, 10, 1251–1269, doi:10.3762/bjnano.10.125

• contains generally four times more catalyst than the anodic layer, which explains why most of the research is focused on the optimization of the cathodic catalytic layer. Platinum nanoparticles (NPs) supported on carbon black (CB), especially Vulcan XC-72 [3][4], are usually used as the catalyst. To meet

Deposition of metal particles onto semiconductor nanorods using an ionic liquid

• Michael D. Ballentine,
• Elizabeth G. Embry,
• Marco A. Garcia and
• Lawrence J. Hill

Beilstein J. Nanotechnol. 2019, 10, 718–724, doi:10.3762/bjnano.10.71

• polar media, platinum nanoparticles were deposited onto these CdSe@CdS nanorods in hydrophobic media based on the photochemical process reported by Alivisatos and coworkers [30], with the liquid component consisting of either toluene/triethylamine or [bmim][Tf2N] (Scheme 1). We chose [bmim][Tf2N] as the

• afforded a mixture of platinum-decorated nanorods and additional platinum nanoparticles that were not attached to CdSe@CdS nanorods. For the platinum deposition conducted in toluene, the unattached platinum particles were removed by several dissolution and precipitation cycles using toluene and ethanol

• (Figure 1). Quantification of the TEM images confirmed that both samples had similarly sized platinum nanoparticles and a similar number of platinum particles per nanorod (Table 1, a minimum of 100 particles were counted/sized in each case). Using this information, we estimated comparable platinum to

Comparative biological effects of spherical noble metal nanoparticles (Rh, Pd, Ag, Pt, Au) with 4–8 nm diameter

• Alexander Rostek,
• Marina Breisch,
• Kevin Pappert,
• Kateryna Loza,
• Marc Heggen,
• Manfred Köller,
• Christina Sengstock and
• Matthias Epple

Beilstein J. Nanotechnol. 2018, 9, 2763–2774, doi:10.3762/bjnano.9.258

• ]. Platinum nanoparticles can be obtained by metal carbonyl-mediated synthesis in organic solvents [81]. Nanoscale platinum catalysts were synthesized using NaBH4 in octylamine [82]. Small gold nanoparticles (<10 nm) can be produced by wet-chemical approaches using strong reductants (e.g., NaBH4) in the

Nanocellulose: Recent advances and its prospects in environmental remediation

• Katrina Pui Yee Shak,
• Yean Ling Pang and
• Shee Keat Mah

Beilstein J. Nanotechnol. 2018, 9, 2479–2498, doi:10.3762/bjnano.9.232

Localized photodeposition of catalysts using nanophotonic resonances in silicon photocathodes

• Evgenia Kontoleta,
• Sven H. C. Askes,
• Lai-Hung Lai and
• Erik C. Garnett

Beilstein J. Nanotechnol. 2018, 9, 2097–2105, doi:10.3762/bjnano.9.198

• spots”. These areas can be used for localized extraction of the photogenerated charges, which in turn could drive chemical reactions for synthesis of catalytic materials. In this work, we use these nanophotonic hot spots in vertical silicon nanowires to locally deposit platinum nanoparticles in a photo

• , known optical constants and broad spectral absorption range. In presence of a Pt-catalyst precursor (H2PtCl6) in a three-electrode photo-electrochemical system (Figure 1), photogenerated electrons reach the surface of the silicon nanowires, reducing the precursor to form metallic platinum nanoparticles

• corresponding photocurrent (Figure S4a, Supporting Information File 1), which means that the electrons reaching the electrolyte by biasing the samples dominate over the photogenerated ones. SEM images (Figure S5, Supporting Information File 1) show the homogenous formation of platinum nanoparticles both on the

A biofunctionalizable ink platform composed of catechol-modified chitosan and reduced graphene oxide/platinum nanocomposite

• Peter Sobolewski,
• Agata Goszczyńska,
• Małgorzata Aleksandrzak,
• Karolina Urbaś,
• Joanna Derkowska,
• Agnieszka Bartoszewska,
• Jacek Podolski,
• Ewa Mijowska and
• Mirosława El Fray

Beilstein J. Nanotechnol. 2017, 8, 1508–1514, doi:10.3762/bjnano.8.151

• , Szczecin, Poland 10.3762/bjnano.8.151 Abstract We present an ink platform for a printable polymer–graphene nanocomposite that is intended for the development of modular biosensors. The ink consists of catechol-modified chitosan and reduced graphene oxide decorated with platinum nanoparticles (rGO–Pt). We

• . First, we prepare dispersions of reduced graphene oxide (rGO) decorated with platinum nanoparticles (rGO–Pt) in ethylene glycol (EG). As the polymer matrix, we utilize chitosan (CHI), a polycationic biopolymer that provides excellent film-forming properties and easy-to-functionalize amine groups [8

Laser irradiation in water for the novel, scalable synthesis of black TiO_x photocatalyst for environmental remediation

• Massimo Zimbone,
• Giuseppe Cacciato,
• Mohamed Boutinguiza,
• Vittorio Privitera and
• Maria Grazia Grimaldi

Beilstein J. Nanotechnol. 2017, 8, 196–202, doi:10.3762/bjnano.8.21

• samples have a surface area of 0.7 cm2. The synthesis of platinum nanoparticles (PtNps) was performed by pulsed laser ablation in liquid by irradiating a Pt metal foil (Sigma Aldrich, purity 99%) with a Nd:YAG laser (Giant G790-30) at 1064 nm (10 ns pulse duration, 10 Hz repetition rate). The laser was

• represented in Figure 1b. Samples for photo-degradation tests were realized by depositing some drops (about 2 mL) of the PtNps solution on the rear side of the titanium foil at 90 °C and waiting for evaporation of the water. A continuous layer of platinum nanoparticles adhered to the substrate is formed

Functionalized platinum nanoparticles with surface charge trigged by pH: synthesis, characterization and stability studies

• Giovanna Testa,
• Laura Fontana,
• Iole Venditti and
• Ilaria Fratoddi

Beilstein J. Nanotechnol. 2016, 7, 1822–1828, doi:10.3762/bjnano.7.175

• Giovanna Testa Laura Fontana Iole Venditti Ilaria Fratoddi Department of Chemistry, University Sapienza of Rome, p.le Aldo Moro 5, 00185 Rome, Italy 10.3762/bjnano.7.175 Abstract In this work, the synthesis and characterization of functionalized platinum nanoparticles (PtNPs) have been

• colloidal system. Keywords: functionalized platinum nanoparticles; pH responsive materials; synthesis of metal nanoparticles; thiol functionalization; Introduction Metal nanoparticles (MNPs), in particular, platinum nanoparticles (PtNPs) offer a wide range of chemico-physical properties that can be of

• stabilizer to protect the platinum nanoparticles [18]. However, an efficient separation of the colloid from solution could be difficult to reach [19]. Among the synthetic approaches, wet chemical synthesis offers the opportunity to introduce a selected functionalization onto the NP surface and generally give

Materials and characterization techniques for high-temperature polymer electrolyte membrane fuel cells

• Roswitha Zeis

Beilstein J. Nanotechnol. 2015, 6, 68–83, doi:10.3762/bjnano.6.8

• carbon nanotubes in a PBI polymer layer covered with platinum nanoparticles. A schematic drawing and TEM images of this innovative catalyst concept are shown in Figure 7. The PBI wrapper serves as an ionomer and binder of the catalyst layer simultaneously. The polymer also glues the platinum

• encapsulate the platinum nanoparticles, resulting in blocking of the catalyst sites for hydrogen oxidation and oxygen reduction. It is even possible to prepare electrodes for high-temperature MEAs without any polymeric binder. The absence of binder material seems to affect the mechanical stability only little

• – μfoil. With various cell potentials, different adsorbates were observed on the platinum nanoparticles as shown in Figure 13. Three potential regions were identified with distinctly different species covering the catalyst surface. At cell potentials lower than 300 mV, hydrogen is adsorbed. In the

Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study

• Pauline Maffre,
• Stefan Brandholt,
• Karin Nienhaus,
• Li Shang,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212

• reliable in our hands. In our original FCS study [45], we investigated the adsorption of human serum albumin (HSA) onto carboxyl-functionalized, polymer-encased iron platinum nanoparticles (Fe–Pt NPs) with a hydrodynamic radius, RH, of 5–6 nm. We prepared HSA solutions of different concentrations in

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

• Sebastian Ahlberg,
• Alexandra Antonopulos,
• Jörg Diendorf,
• Ralf Dringen,
• Matthias Epple,
• Rebekka Flöck,
• Wolfgang Goedecke,
• Christina Graf,
• Nadine Haberl,
• Jens Helmlinger,
• Fabian Herzog,
• Frederike Heuer,
• Stephanie Hirn,
• Christian Johannes,
• Stefanie Kittler,
• Manfred Köller,
• Katrin Korn,
• Wolfgang G. Kreyling,
• Fritz Krombach,
• Jürgen Lademann,
• Kateryna Loza,
• Eva M. Luther,
• Marcelina Malissek,
• Martina C. Meinke,
• Daniel Nordmeyer,
• Anne Pailliart,
• Jörg Raabe,
• Fiorenza Rancan,
• Barbara Rothen-Rutishauser,
• Eckart Rühl,
• Carsten Schleh,
• Andreas Seibel,
• Christina Sengstock,
• Lennart Treuel,
• Annika Vogt,
• Katrin Weber and
• Reinhard Zellner

Beilstein J. Nanotechnol. 2014, 5, 1944–1965, doi:10.3762/bjnano.5.205

• further studies are needed to reveal the molecular uptake mechanism(s). FIB/SEM analysis represents a valuable technique to proof the nanoparticle uptake as was similarly shown by Pelka et al. [85] with HT29 cells (colon carcinoma cells) and platinum nanoparticles. Thus, FIB/SEM which presents a technique

Enhanced photocatalytic hydrogen evolution by combining water soluble graphene with cobalt salts

• Jing Wang,
• Ke Feng,
• Hui-Hui Zhang,
• Bin Chen,
• Zhi-Jun Li,
• Qing-Yuan Meng,
• Li-Ping Zhang,
• Chen-Ho Tung and
• Li-Zhu Wu

Beilstein J. Nanotechnol. 2014, 5, 1167–1174, doi:10.3762/bjnano.5.128

• demonstrated that G-SO3 acts as an electron mediator of EY and platinum nanoparticles co-catalyst, we consider that in the current study the electron transfer process from the EY radical anion (EY•−) to G-SO3 or in situ formed-Co(TEOA)22+ would be facilitated. Similar to the storage phenomenon observed in

Design criteria for stable Pt/C fuel cell catalysts

• Josef C. Meier,
• Carolina Galeano,
• Ioannis Katsounaros,
• Jonathon Witte,
• Hans J. Bongard,
• Angel A. Topalov,
• Claudio Baldizzone,
• Stefano Mezzavilla,
• Ferdi Schüth and
• Karl J. J. Mayrhofer

Beilstein J. Nanotechnol. 2014, 5, 44–67, doi:10.3762/bjnano.5.5

• nm and two Pt@HGS catalysts with different particle size, 1–2 nm and 3–4 nm. Specifically, Pt@HGS corresponds to platinum nanoparticles incorporated and confined within the pore structure of the nanostructured carbon support, i.e., hollow graphitic spheres (HGS). All three materials are characterized

• , Pt@HGS 1–2 nm and Pt@HGS 3–4 nm (with Pt@HGS meaning platinum nanoparticles confined within the carbon support HGS) and compare the results with the performance of other conventional fuel cell catalysts. In this context, we will evaluate possible causes for the previously reported excellent stability

• ]. Because of the large surface area and the mesoporous structure, the platinum deposition results in a high dispersion of platinum particles within the network with platinum nanoparticles in a size range of approximately 1–2 nm (Pt@HGS 1–2 nm). An increase in particle size was possible through a thermal

Functionalization of vertically aligned carbon nanotubes

• Eloise Van Hooijdonk,
• Carla Bittencourt,
• Rony Snyders and
• Jean-François Colomer

Beilstein J. Nanotechnol. 2013, 4, 129–152, doi:10.3762/bjnano.4.14

• recently, the functionalization of VA-CNTs arrays with platinum nanoparticles was examined by Soin et al. [121]. A method combining microwave-plasma-enhanced chemical vapor deposition and DC sputtering was employed in order to synthesize such samples. The alignment of tubes was not perturbed, no physical

• distribution along the length of the tube, since defects are nucleation sites for NP growth [122]. Functionalization of VA-CNT arrays with platinum nanoparticles is promising in fuel-cell development [123]. Similar samples, i.e., platinum decorated VA-CNTs, were produced by Dameron et al. [124] using atomic

Platinum nanoparticles from size adjusted functional colloidal particles generated by a seeded emulsion polymerization process

• Nicolas Vogel,
• Ulrich Ziener,
• Achim Manzke,
• Alfred Plettl,
• Paul Ziemann,
• Johannes Biskupek,
• Clemens K. Weiss and
• Katharina Landfester

Beilstein J. Nanotechnol. 2011, 2, 459–472, doi:10.3762/bjnano.2.50

• and functionalities. Size-adjusted platinum-acetylacetonate containing latex particles with identical seed particles and varied shell thicknesses are used to produce arrays of highly ordered platinum nanoparticles with different interparticle distances but identical particle sizes. For that, a self

• saturation state, the type of surfactant, the amount of precursor loading and the size of the colloids are varied. By short annealing at high temperatures platinum nanoparticles are generated from the saturated state particles. Typically, the present fabrication method delivers a maximum interparticle

• distance of about 260 nm for well-defined crystalline platinum nanoparticles limited by deformation processes due to softening of the organic material during the plasma applications. Keywords: colloid lithography; functional colloids; miniemulsion polymerization; nanoparticles; seeded emulsion